This collection of 8 essays introduces literary and cultural theorists into the domain of operatic textual analysis, long the exclusive preserve of musicologists. The contributors include some of the most distinguished critics of the past 30 years, most of them writing about opera for the first time.

This book taps the best American thinkers to answer the essential American question: How do we sustain our experiment in government of, by, and for the people? Authored by an extraordinary and politically diverse roster of public officials, scholars, and educators, these chapters describe our nation's civic education problem, assess its causes, offer an agenda for reform, and explain the high stakes at risk if we fail.

The recent publication by Wylie et al. is reviewed, demonstrating that the p53 protein regulates the movement of transposons. While this work presents genetic evidence for a piRNA‐mediated p53 interaction with transposons in Drosophila and zebrafish, it is herein placed in the context of a decade or so of additional work that demonstrated a role for p53 in regulating transposons and other repetitive elements. The line of thought in those studies began with the observation that transposons damage DNA and p53 (...) regulates DNA damage. The presence of transposon movement can increase the rate of evolution in the germ line and alter genes involved in signal transduction pathways. Transposition can also play an important role in cancers where the p53 gene function is often mutated. This is particularly interesting as recent work has shown that de‐repression of repetitive elements in cancer has important consequences for the immune system and tumor microenvironment. (shrink)

We describe a solution to the redundancy problem related to that proposed in Feldman & Levin's target article. We suggest that the system may use a fixed mapping between commands organized at the level of degrees of freedom and commands to individual muscles. This proposal eliminates the need to maintain an explicit representation of musculoskeletalgeometry in planning movements.

Collected and edited by Noah Levin -/- Table of Contents: -/- UNIT ONE: INTRODUCTION TO CONTEMPORARY ETHICS: TECHNOLOGY, AFFIRMATIVE ACTION, AND IMMIGRATION 1 The “Trolley Problem” and Self-Driving Cars: Your Car’s Moral Settings (Noah Levin) 2 What is Ethics and What Makes Something a Problem for Morality? (David Svolba) 3 Letter from the Birmingham City Jail (Martin Luther King, Jr) 4 A Defense of Affirmative Action (Noah Levin) 5 The Moral Issues of Immigration (B.M. Wooldridge) 6 (...) The Ethics of our Digital Selves (Noah Levin) -/- UNIT TWO: TORTURE, DEATH, AND THE “GREATER GOOD” 7 The Ethics of Torture (Martine Berenpas) 8 What Moral Obligations do we have (or not have) to Impoverished Peoples? (B.M. Wooldridge) 9 Euthanasia, or Mercy Killing (Nathan Nobis) 10 An Argument Against Capital Punishment (Noah Levin) 11 Common Arguments about Abortion (Nathan Nobis & Kristina Grob) 12 Better (Philosophical) Arguments about Abortion (Nathan Nobis & Kristina Grob) -/- UNIT THREE: PERSONS, AUTONOMY, THE ENVIRONMENT, AND RIGHTS 13 Animal Rights (Eduardo Salazar) 14 John Rawls and the “Veil of Ignorance” (Ben Davies) 15 Environmental Ethics: Climate Change (Jonathan Spelman) 16 Rape, Date Rape, and the “Affirmative Consent” Law in California (Noah Levin) 17 The Ethics of Pornography: Deliberating on a Modern Harm (Eduardo Salazar) 18 The Social Contract (Thomas Hobbes) -/- UNIT FOUR: HAPPINESS 19 Is Pleasure all that Matters? Thoughts on the “Experience Machine” (Prabhpal Singh) 20 Utilitarianism (J.S. Mill) 21 Utilitarianism: Pros and Cons (B.M. Wooldridge) 22 Existentialism, Genetic Engineering, and the Meaning of Life: The Fifths (Noah Levin) 23 The Solitude of the Self (Elizabeth Cady Stanton) 24 Game Theory, the Nash Equilibrium, and the Prisoner’s Dilemma (Douglas E. Hill) -/- UNIT FIVE: RELIGION, LAW, AND ABSOLUTE MORALITY 25 The Myth of Gyges and The Crito (Plato) 26 God, Morality, and Religion (Kristin Seemuth Whaley) 27 The Categorical Imperative (Immanuel Kant) 28 The Virtues (Aristotle) 29 Beyond Good and Evil (Friedrich Nietzsche) 30 Other Moral Theories: Subjectivism, Relativism, Emotivism, Intuitionism, etc. (Jan F. Jacko). (shrink)

The arts of rule cover the exercise of power by princes and popular sovereigns, but they range beyond the domain of government itself, extending to civil associations, political parties, and religious institutions. Making full use of political philosophy from a range of backgrounds, this festschrift for Harvey Mansfield recognizes that although the arts of rule are comprehensive, the best government is a limited one.

At any given time, a subject has a multiplicity of conscious experiences. A subject might simultaneously have visual experiences of a red book and a green tree, auditory experiences of birds singing, bodily sensations of a faint hunger and a sharp pain in the shoulder, the emotional experience of a certain melancholy, while having a stream of conscious thoughts about the nature of reality. These experiences are distinct from each other: a subject could experience the red book without the singing (...) birds, and could experience the singing birds without the red book. But at the same time, the experiences seem to be tied together in a deep way. They seem to be unified, by being aspects of a single encompassing state of consciousness. (shrink)

In this essay we reflect critically on how animal ethics, and in particular thinking about moral standing, is currently configured. Starting from the work of two influential “analytic” thinkers in this field, Peter Singer and Tom Regan, we examine some basic assumptions shared by these positions and demonstrate their conceptual failings—ones that have, despite efforts to the contrary, the general effect of marginalizing and excluding others. Inspired by the so-called “continental” philosophical tradition , we then argue that what is needed (...) is a change in the rules of the game, a change of the question. We alter the normative question from “What properties does the animal have?” to “What are the conditions under which an entity becomes a moral subject?” This leads us to consider the role of language, personal relations, and material-technological contexts. What is needed then in response to the moral standing problem, is not more of the same—yet another, more refined criterion and argumentation concerning moral standing, or a “final” rational argumentation that would be able to settle the animal question once and for all—but a turning or transformation in both our thinking about and our relations to animals, through language, through technology, and through the various place-ordering practices in which we participate. (shrink)

The scope of noninvasive prenatal testing (NIPT) could expand in the future to include detailed analysis of the fetal genome. This will allow for the testing for virtually any trait with a genetic contribution, including “non-medical” traits. Here we discuss the potential use of NIPT for these traits. We outline a scenario which highlights possible inconsistencies with ethical decision-making. We then discuss the case against permitting these uses. The objections include practical problems; increasing inequities; increasing the burden of choice; negative (...) impacts on the child, family, and society; and issues with implementation. We then outline the case for permitting the use of NIPT for these traits. These include arguments for reproductive liberty and autonomy; questioning the labeling of traits as “non-medical”; and the principle of procreative beneficence. This summary of the case for and against can serve as a basis for the development of a consistent and coherent ethical framework. (shrink)

An important function of the self is to identify external objects that are potentially personally relevant. We suggest that such objects may be identified through mere ownership. Extant research suggests that encoding information in a self-relevant context enhances memory , thus an experiment was designed to test the impact of ownership on memory performance. Participants either moved or observed the movement of picture cards into two baskets; one of which belonged to self and one which belonged to another participant. A (...) subsequent recognition test revealed that there was a significant memory advantage for objects that were owned by self. Acting on items had no impact on memory. Results are discussed with reference to the importance of self-object associations in cognition. (shrink)

This study explored calibrating a large item bank for use in multidimensional health measurement with computerized adaptive testing, using both item responses and response time (RT) information. The Activity Measure for Post-Acute Care is a patient-reported outcomes measure comprised of three correlated scales (Applied Cognition, Daily Activities, and Mobility). All items from each scale are Likert type, so that a respondent chooses a response from an ordered set of four response options. The most appropriate item response theory model for analyzing (...) and scoring these items is the multidimensional graded response model (MGRM). During the field testing of the items, an interviewer read each item to a patient and recorded, on a tablet computer, the patient’s responses and the software recorded RTs. Due to the large item bank with over 300 items, data collection was conducted in four batches with a common set of anchor items to link the scale. Van der Linden’s (2007) hierarchical modeling framework was adopted. Several models, with or without interviewer as a covariate and with or without interaction between interviewer and items, were compared for each batch of data. It was found that the model with the interaction between interviewer and item, when the interaction effect was constrained to be proportional, fit the data best. Therefore, the final hierarchical model with lognormal model for RT and the MGRM for response data was fitted to all batches of data via a concurrent calibration. Evaluation of parameter estimates revealed that (1) adding response time information did not affect the item parameter estimates and their standard errors significantly; (2) adding response time information helped reduce the standard error of patients’ multidimensional latent trait estimates, but adding interviewer as a covariate did not result in further improvement. Implications of the findings for follow up adaptive test delivery design are discussed. (shrink)

In this seminal work, acclaimed philosopher Bernhard Waldenfels deals with the problem of the nature of order after the “shattering of the world,” and the loss of the idea of a universal or fundamental order._ _ Order in the Twilight__ unites phenomenological methodology with recent work on the theory of order, normativity, and dialogue, as well as structuralism and Gestalt theory. Philosophically stringent, it expresses a more optimistic attitude than much modern philosophy, especially deconstruction._ Waldenfels passes the question of order (...) through numerous defining aspects, and concludes that there is not one global order, but rather various conflicting domains of order. Whenever the boundary of a vital or experiential domain is crossed, a discourse speaks at the boundary, not about it, and across a threshold without abolishing it. The rest is rationalization, i.e., an attempt to find a place in the respective order for what is to-be-ordered. But why, the author concludes, should a theory be more unambiguous than reality? _ Order in the Twilight__ is an important book at this time, because it may help lift the humanities out of the skeptical, relativistic disarray in which they have been embroiled in recent decades. Waldenfels does not attempt to dictate what reality should be; rather, he is open to any valid evidences. His book offers a solid footing to the human and social sciences as they seek to escape from deconstructive irrationalism. (shrink)

David and Mary Norton present the definitive scholarly edition of one of the greatest philosophical works ever written. This second volume begins with their 'Historical Account' of the Treatise, an account that runs from the beginnings of the work to the period immediately following Hume's death in 1776, followed by an account of the Nortons' editorial procedures and policies and a record of the differences between the first-edition text of the Treatise and the critical text that follows. The volume (...) continues with an extensive set of 'Editors' Annotations', intended to illuminate Hume's texts; a four-part bibliography of materials cited in both volumes; and a comprehensive index. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Jewish Thought and Scientific Discovery in Early Modern EuropeNoah J. EfronAlmost a quarter-century ago Benjamin Nelson published his famous plea for what he called a “differential” and “comparative historical sociology of ‘science’ in civilizational perspective.” 1 Like Max Weber, Robert Merton, and Joseph Needham, Nelson believed that the growth of western science could be better understood when compared to the ways “science” fared in other cultures with other intellectual (...) and institutional and economic sensibilities and structures. A particularly propitious case study for such a differential and comparative historical study of science, as Hillel Levine observed in his 1983 essay about Jewish reactions to heliocentrism, are the Jews of early modern Europe, who constituted “a society geographically and culturally contiguous with those who framed and advanced occidental ‘science.’” 2Since about the time of Nelson’s plea, David B. Ruderman has been writing the history of Jewish attitudes towards, and engagements with, science during the period in which modern western science was constituting itself. It is no exaggeration to say that he established this as a field of study, producing a steady stream of historical studies, initially of Italian Jews who read and wrote about nature and its study, but continually expanding his compass. 3 The field [End Page 719] Ruderman established and the studies he produced have been “repercussive” (to borrow his own adjective) in many directions—shedding light on Jewish-Christian relations, on early-modern Jewish intellectual history, on the deployments of Kabbalah and magic in early modern times, and so on. One of Ruderman’s achievements—perhaps not the most important in his view (for he considers himself a historian of Jewish thought and culture and not a historian of science) but of great importance nonetheless—has been to begin to lay the groundwork for a comparative history of Jewish and Christian attitudes towards and participation in the “new sciences.”Ruderman’s newest book is a big step towards Nelson’s desideratum, using Jewish attitudes as the comparative case. It is a collection of twelve linked essays (five of which have appeared elsewhere in one form or another) framed by a synthetic introduction and epilogue. The essays are individual or group portraits of Jews who evinced interest in natural philosophy or medicine, in a variety of settings and for a variety of reasons, between the sixteenth and eighteenth centuries. Ruderman describes his subject as “three distinct but interrelated groups among early modern Jews”: (1) “converso physicians and other university-trained intellectuals who fled Spain and Portugal in the seventeenth century and settled in Holland, Italy, Germany, England, and even eastern Europe, serving as doctors and purveyors of scientific learning throughout the Jewish communities of Europe, while yielding considerable political and economic power,” (2) “certain circles of Jewish scholars in central and eastern Europe [who] pursued scientific learning, especially astronomy, in more informal settings as a desirable supplement to rabbinic study,” and (3) “the hundreds of Jews who attended Italian medical schools, primarily the University of Padua, from the late sixteenth through the eighteenth centuries.” 4In fact Ruderman covers even more ground than this. As background, he includes a brief essay on the attitudes of tenth- to fifteenth-century Jews towards nature and its study, surely the best survey of the sort available. Of the thirty or so early modern Jews that he describes in the remainder of the book, about twenty fit in at least one of the three camps upon which he focuses. 5 Nine [End Page 720] emerged from different circumstances (though these too were often highly influenced by one or more of the focus populations). This fact does nothing to impugn Ruderman’s typology—the groups he described were, in fact, of particular importance, and his identification of them as the principle populations contemplating and promulgating natural philosophy among Jews is in itself an advance of some moment. But the fact that a third of the cases Ruderman described do not fit into his own typology is testimony both to the complexity of his subject, and to his agility in addressing it.By anthologizing a dozen depictions of different thinkers in different milieus, Ruderman affords what might be called a “hawk... (shrink)

Although A-consciousness and P-consciousness are conceptually distinct, a refined notion of A-consciousness makes it plausible that the two are empirically inseparable. I suggest that the notion of direct availability for global control can play a central role here, and draw out some consequences.

Introduction: making the invisible visible -- The nobility of the material -- Research at war -- The guilded age of research -- The doctor as whistle-blower -- New rules for the laboratory -- Bedside ethics -- The doctor as stranger -- Life through death -- Commissioning ethics -- No one to trust -- New rules for the bedside -- Epilogue: The price of success.

[This is an edited version of a keynote talk at the conference on Neural Information Processing Systems (NeurIPS) on November 28, 2022, with some minor additions and subtractions.] -/- There has recently been widespread discussion of whether large language models might be sentient or conscious. Should we take this idea seriously? I will break down the strongest reasons for and against. Given mainstream assumptions in the science of consciousness, there are significant obstacles to consciousness in current models: for example, their (...) lack of recurrent processing, a global workspace, and unified agency. At the same time, it is quite possible that these obstacles will be overcome in the next decade or so. I conclude that while it is somewhat unlikely that current large language models are conscious, we should take seriously the possibility that successors to large language models may be conscious in the not-too-distant future. (shrink)

The physician-patient relationship has changed over the last several decades, requiring a systematic reevaluation of the competing demands of patients, physicians, and families. In the era of genetic testing, using a model of patient care known as the family covenant may prove effective in accounting for these demands. The family covenant articulates the roles of the physician, patient, and the family prior to genetic testing, as the participants consensually define them. The initial agreement defines the boundaries of autonomy and benefit (...) for all participating family members. The physician may then serve as a facilitator in the relationship, working with all parties in resolving potential conflicts regarding genetic information. The family covenant promotes a fuller discussion of the competing ethical claims that may come to bear after genetic test results are received. (shrink)

‘‘Undone science’’ refers to areas of research that are left unfunded, incomplete, or generally ignored but that social movements or civil society organizations often identify as worthy of more research. This study mobilizes four recent studies to further elaborate the concept of undone science as it relates to the political construction of research agendas. Using these cases, we develop the argument that undone science is part of a broader politics of knowledge, wherein multiple and competing groups struggle over the construction (...) and implementation of alternative research agendas. Overall, the study demonstrates the analytic potential of the concept of undone science to deepen understanding of the systematic nonproduction of knowledge in the institutional matrix of state, industry, and social movements that is characteristic of recent calls for a ‘‘new political sociology of science.’’. (shrink)

Against prevailing interpretations, this article contends that Plato's Sophist and Statesman accord the sophist a kind of ‘knowing-how’ (epistêmê). In Soph. 233c10‒d2, the Visitor and Theaetetus agree that the sophist has not truth but a δοξαστικὴ ἐπιστήμη. This phrase cannot mean ‘a seeming knowledge’, for –ικός adjectives formed from verbs express the ability to perform the action denoted by the verb—here, δοξάζω. Although not a first-order, subject-area knowledge, sophistry is a second-order knowledge of how to form and use judgements (doxai). (...) Other acknowledgements of the sophist's epistêmê and the ascription to him of τέχνη, ‘craft/expertise’, confirm that the Visitor's conclusion is not to be dismissed as irony. To critics who argue from the Gorgias and from other works that Plato must consider the Visitor's conclusion an error, the author replies: 1) other dialogues do not control the Visitor dialogues; 2) the Visitor does not validly demonstrate that the sophist lacks all knowledge; 3) by admitting sensibles into Being, the Visitor and Theaetetus allow the objects of epistêmê to include things in the embodied world, even likenesses. Non-philosophers’ epistêmê in the Visitor dialogues is not implicated in the difficulties that critics have raised about epistemology in the so-called Two Worlds dialogues. On this new ontology, even the sophist, if guided by philosophical rulers, can benefit citizens by employing his elenctic expertise as Socrates did, aiding their growth toward virtue. (shrink)

There is a long tradition in philosophy of using a priori methods to draw conclusions about what is possible and what is necessary, and often in turn to draw conclusions about matters of substantive metaphysics. Arguments like this typically have three steps: first an epistemic claim , from there to a modal claim , and from there to a metaphysical claim.

A complete sourcebook for philosophical discussion of the nature of function in biology.

Taking a social identity approach to health behaviors, this research examines whether experimentally “activating” the human identity is an effective public-health strategy to curb the spread of COVID-19. Three goals of the research include examining: whether the human identity can be situationally activated using an experimental manipulation, whether activating the human identity causally increases behavioral intentions to protect the self and others from COVID-19, and whether activating the human identity causally increases behaviors that help protect vulnerable communities from COVID-19. Across (...) two preregistered experiments, results suggest the manipulation of identification with humanity had a significant but small effect on participants’ psychological bond with all humanity, but not their concern for all humanity. However, the manipulation had no causal effect on health-related behavioral intentions or helping behaviors that reduce the spread of COVID-19. Limitations, future directions, and direct benefits of the research are discussed. (shrink)

This appeared in Philosophy and Phenomenological Research 59:473-93, as a response to four papers in a symposium on my book The Conscious Mind . Most of it should be comprehensible without having read the papers in question. This paper is for an audience of philosophers and so is relatively technical. It will probably also help to have read some of the book. The papers I’m responding to are: Chris Hill & Brian McLaughlin, There are fewer things in reality than are (...) dreamt of in Chalmers’ philosophy Brian Loar, David Chalmers’ The Conscious Mind Sydney Shoemaker, On David Chalmers’ The Conscious Mind Stephen Yablo, Concepts and consciousness Contents. (shrink)

Is conceptual analysis required for reductive explanation? If there is no a priori entailment from microphysical truths to phenomenal truths, does reductive explanation of the phenomenal fail? We say yes . Ned Block and Robert Stalnaker say no.

There has been much interest in the possibility of connectionist models whose representations can be endowed with compositional structure, and a variety of such models have been proposed. These models typically use distributed representations that arise from the functional composition of constituent parts. Functional composition and decomposition alone, however, yield only an implementation of classical symbolic theories. This paper explores the possibility of moving beyond implementation by exploiting holistic structure-sensitive operations on distributed representations. An experiment is performed using Pollack’s Recursive (...) Auto-Associative Memory. RAAM is used to construct distributed representations of syntactically structured sentences. A feed-forward network is then trained to operate directly on these representations, modeling syn- tactic transformations of the represented sentences. Successful training and generalization is obtained, demonstrating that the implicit structure present in these representations can be used for a kind of structure-sensitive processing unique to the connectionist domain. (shrink)